Cafeína: Factor protector en la diabetes

Autores/as

Zorayda Urzúa García
Universidad de Colima

Palabras clave:

cafeína, diabetes mellitus tipo 2, glucosa sanguínea, modelo experimental

Sinopsis

La presente obra se enfoca en el estudio de la cafeína como factor protector en la diabetes mellitus tipo 2, descrita desde la perspectiva de la metodología cuantitativa, con un estudio experimental del área de la biomedicina y donde se utilizaron ratas sanas y con diabetes mellitus experimental, respetando siempre las normas éticas hacia estos seres que nos proporcionan un gran avance al conocimiento. La diabetes mellitus es una enfermedad prevenible en periodos iniciales (pre-diabetes), pero una vez instaurada es incurable. Se ofrecen respuestas a los cuestionamientos sobre los beneficios de la cafeína en la prevención de dicha enfermedad.

Descargas

Los datos de descarga aún no están disponibles.

Biografía del autor/a

Zorayda Urzúa García, Universidad de Colima

Doctora en ciencias médicas por la Universidad de Colima, ganadora del Premio Estatal de la Juventud en 2010 en el área de investigación y desarrollo tecnológico y en 2013 en el área de actividades académicas. Pertenece al SNI. Sus líneas de investigación son la biomedicina y medicina preventiva de las enfermedades crónico degenerativas como la diabetes mellitus tipo 2 y sus complicaciones, así como el síndrome metabólico. Ha publicado en revistas internacionales. Actualmente está adscrita a la Unidad de Medicina Familiar 19 (Departamento de DIABETIMSS) y al Hospital General de Zona No. 1 del IMSS Colima.

Referencias

Abdul-Ghani, M.; DeFronzo, R.; Williams, K.; Stern, M. (2007). What is the best predictor of future type 2 diabetes? Diabetes Care, 30: 1544-1548. https://doi.org/10.2337/dc06-1331

American Diabetes Association (2010). Diagnosis and classification diabetes mellitus. Diabetes care, 28: 37-42. https://doi.org/10.2337/diacare.28.suppl_1.S37

Bhandari, B.K.; Feliers, D.; Duraisamy, S. et al. (2001). Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells. Kidney Inernational, 59: 866-875. https://doi.org/10.1046/j.1523-1755.2001.059003866.x

Benowitz, N.L. (1990). Clinical pharmacology of caffeine. Annual Review Medical, 41: 377-388. https://doi.org/10.1146/annurev.me.41.020190.001425

Blanco, A. (2006). Química biológica. Ed. El Ateneo.

Breyer, M.D.; Böttinger, E.; Brosius, F.C.; et al. (2005). Mouse models of diabetic nephropathy. Journal of American Society Nephrol., 16: 27-45. https://doi.org/10.1681/ASN.2004080648

Campos, H. y Baylin, A. (2007). Coffe consumption and risk of type 2 diabetes and heart disease. Nutrition Review, 65(4): 173-179. https://doi.org/10.1301/nr.2007.apr.173-179

Castro, L. (1977). Diseño experimental sin estadística: Usos y restricciones en su aplicación a las ciencias de la conducta. 2a edición (9ª reimpresión, 1992). México: Editorial Trillas.

Cheraskin, E. y Ringsdorf, W.M.Jr. (1967). Efecto of caffeine versus placebo supplementation on blood-glucose concentration. Lancet., 2: 1299-1300. https://doi.org/10.1016/S0140-6736(67)91593-0

Cheraskin, E. y Ringsdorf, W.M.Jr. (1968). Blood-glucose levels after caffeine. Letters to the editor. Lancet., 2: 689. https://doi.org/10.1016/S0140-6736(68)92550-6

Currie, R.A.; Walker, K.S.; Gray, A. et al. (1999). Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase. Biochemical Journal., 337: 575- 583. https://doi.org/10.1042/bj3370575

Dawson-Saunders, B. y Trapp, R.G. (2005). Bioestadística Médica. 5ª Ed. México: El Manual Moderno.

De Fronzo, R.A. (2004). Pathogenesis of type 2 diabetes mellitus. Medical Clinical North America, 88: 787-832. https://doi.org/10.1016/j.mcna.2004.04.013

De Jong, J.W.; De Jonge, R.; Keijzer, E. y Brandamante, S. (2000). The role of adenosine in preconditioning. Pharmacological therapeutics, 87: 141-149. https://doi.org/10.1016/S0163-7258(00)00044-9

Denaro, C.P.; Brown, C.R.; Wilson, M.; Jacob, P.III y Benowitz, N.L. (1990). Dose-dependence of caffeine metabolism with repeated dosing. Clinical Pharmacological Therapeutics, 48: 277-285. https://doi.org/10.1038/clpt.1990.150

Donovan, J.L. y DeVane, C.L. (2001). A primer on caffeine pharmacology and its drug interaction in clinical psychopharmacology. Psychopharmacology Bulletin, 35 (3): 30-48. https://doi.org/10.64719/pb.4252

Duff, G. (2007). Expert scientific group in phase on clinical trials. Final report. 26-30.

Egawa, T.; Hamada, T.; Karaike, X.; Kameda, N.; Masuda, S.; Iwanaka, N. y Hayashi, T. (2010). Caffeine activates preferentially a1-Isoform of 5'-AMP -ac- tivated protein kinase in rat skeletal muscle. Acta Physiologica. En prensa.

Federación Mexicana de Diabetes. (2010). Diabetes en números: Los números de la diabetes en México. México: FMD, A.C.

Feinberg, L.J.; Sandberg, H.; De Castro, O. y Bellet, S. (2008). Effects of coffee ingestion on oral glucose tolerance curves in normal human subjects. Metabolism., 17: 916-922. https://doi.org/10.1016/0026-0495(68)90158-3

Flagg, T.; Enkvetchakul, D.; Koster, J. y Nichols, C. (2010). Muscle KATP Channels: recent Insights to energy sensing and myoprotection. American Physi- ological society. Physiological Review, 90: 799-820. https://doi.org/10.1152/physrev.00027.2009

Flakoll, P.J.; Carlson, M.G. y Cherrington, A.D. (2003). Acción fisiológica de la insulina. En: Le Roith, D.; Taylor, S.I. y Olefsky, J.M. (editores), Diabetes mellitus, fundamentos y clínica. 2ª ed. México: Mc Graw Hill.

Fredholm, B.B. (2010). Adenosine receptors as drug targets. Exp Cell Res., 316 (8): 1284-1288. https://doi.org/10.1016/j.yexcr.2010.02.004

Frode, T.S. y Madeiros, Y.S. (2008). Animals models to test drugs with potential antidiabetic activity. Journal of Ethnopharmacology, 115: 173-183. https://doi.org/10.1016/j.jep.2007.10.038

Fuhr, U. y Rost, K.L. (1994). Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva. Pharmacogenetics, 4: 109-116. https://doi.org/10.1097/00008571-199406000-00001

Giovannone, B.; Scaldaferri, M.L.; Federici, M. et al. (2000). Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling poten- tial. Diabetes Metabol Research Review, 16: 434-441. https://doi.org/10.1002/1520-7560(2000)9999:9999<::AID-DMRR159>3.0.CO;2-8

Gong, H.; Simmons, M.S.; Tashkin, D.P.; Hui, K.K. y Lee, E.Y. (1986). Bronchodilator effects of caffeine in coffee. Chest., 89: 335-342.

Graham, T.E.; Sathasivam, P.; Rowland, M.; Marko, N.; Greer, F. y Battram, D. (2001). Caffeine ingestion elevates plasma insulin response in humans during an oral glucose tolerance test. Canadian Journal Physiological Pharmacol., 79: 559-565. https://doi.org/10.1139/y01-026

Han, B.; Hao, C.; Tchekneva, E.; Wang, Y.; Lee, C.; Ebraim, B.; Harris, R.; Kern,T.; Wasserman, D.; Breyer, M. y Qi, Z. (2008). Markers of glycemic control in the mouse: Comparision of six hours and overweight fasted blood glucose to HbA1c. American Journal of Physiological Endocrinology Metabol., 295 (4): 981-986. https://doi.org/10.1152/ajpendo.90283.2008

Hanley, A.; Williams, K.; González, C.; Agostino, R.; Wagenknecht, L.; Stern, M. y Haffner, S. (2003). Prediction of type 2 diabetes using simple measures of insulin resistance. Diabetes, 52: 463-469. https://doi.org/10.2337/diabetes.52.2.463

Higdon, J.V. y Frei, B. (2006). Coffe and health: a review of recent human research. Cit. Rev. Food Science Nutrition, 46 (2): 101-123.

Hino, A.; Adachi, H.; Enomoto, M.; Furuki, K.; Shigetoh, Y.; Ohtsuka, M.; Kumagae, S.; Hirari, Y.; Satoh, A. y Imaizumi, T. (2007). Habitual coffee but not green tea consumption is inversely associated with metabolic syndrome: an epidemiological study in a general Japanese population. Diabe- tes Research Clinical Practice, 76 (3): 383-389. https://doi.org/10.1016/j.diabres.2006.09.033

Horrigan, L.A.; Kelly, J.P. y Connor, T.J. (2006). Inmunomodulatory effects of caffeine: Friend or foe? Journal of Pharmacology and therapeutics, 111: 877- 892. https://doi.org/10.1016/j.pharmthera.2006.02.002

International Coffee Organization (2008). History Coffee Statistics. London, UK: International Coffee Organization. Disponible en: http://eurlex.europa. eu/LexUriServ/site/es/oj/2002/.pdf.

Iso, H.; Date, C.; Wakai, K.; Fukui, M.; et al. (2006). The relation between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults. American College of Physicians, 144 (8): 554-562. https://doi.org/10.7326/0003-4819-144-8-200604180-00005

Joshida, Y.; Hayakawa, M. y Etsuo, N. (2008). Evaluation of the antioxidant effects coffee and its components using biomarkers Hidroxyoctadecadienoic Acid and Isoprostane. Journal of Oleo Science, 57 (12): 691-697. https://doi.org/10.5650/jos.57.691

Kagami, K.; Morita, H.; Onda, K.; Hirano, T. y Oka, K. (2008). Protective effect of caffeine on streptozotocin-induced beta-cell damage in rats. Journal of Pharmacy and pharmacology, 60: 1161-1165. https://doi.org/10.1211/jpp.60.9.0007

Khan, C.R. (1994). Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes, 43: 1066-1084. https://doi.org/10.2337/diab.43.8.1066

Kanety, H.; Moshe, S. y Shafrir, E. (1994). Hyperinsulinemia induces a reversible impairment in insulin receptor function leading to diabetes in te sand rat model of non- insulindependent diabetes mellitus. Proc. Natl. Acad. Sci. USA, 91: 1853-1857. https://doi.org/10.1073/pnas.91.5.1853

Katsumata, K.; Katsumata, K.Jr. y Katsumata, Y. (1992). Protective effect of diltiazem hydrochloride on the occurrence of alloxan or streptozotocin induced diabetes in rats. Hormone Metabolic Research, 24: 508-510. https://doi.org/10.1055/s-2007-1003376

Kerry, B.; Goralski, C.; y Sinal, J. (2007). Type 2 diabetes and cardiovascular disease: getting to the fat of the matter. Canadian Journal Physiology and Pharmacology, 85: 113-132. https://doi.org/10.1139/y06-092

King, H.; Aubert, R. y Herman, W. (1998). Global burden of diabetes, 1995- 2025. Prevalence, numerical estimates and projections. Diabetes Care, 21: 1414-1431. https://doi.org/10.2337/diacare.21.9.1414

Kempf, K.; Herder, Ch.; Erlund, I.; Kolb, H.; Martin, S. y Koening, W. (2010). Effects of coffee consuption on subclinical inflamation and other risk factors for type 2 diabetes: A clinical trial. The American Journal of Clinical Nutrition, 91: 950-957. https://doi.org/10.3945/ajcn.2009.28548

Kirk, R.F. (1982). Experimental design: procedures for the behavioral sciences. 2nd ed. Brooks/Cole.

Knowler, W.C.; Barrett-Connor, E.; Fowler, S.E.; et al. (2002). Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. New England Journal Medical, 346: 393-403. https://doi.org/10.1056/NEJMoa012512

Kohjiro, U.; Fruman, D.A.; et al. (2002). Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-Kinase regulates cell signaling and survival. Molecular Cell Biology, 22: 965-977. https://doi.org/10.1128/MCB.22.3.965-977.2002

Larsen, M.O.; Rolin, B.; Gotfredsen, C.F.; Carr, R.D. y Holst, J.J. (2004). Reduction of beta cell mass: partial insulin secretor y compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig ofter oral glucose in vivo and in the perfused pancreas. Diabetology, 47: 1873-1878. https://doi.org/10.1007/s00125-004-1546-9

Lazar, M.A. (2005). How obesity causes diabetes: not a tell tale. Science, 307: 373-375. https://doi.org/10.1126/science.1104342

Lundsberg, L.S. (1998). Coffeine consumption. En: Spiller, G.A. (ed.), Caffeine. Boca Raton, FL: CRC Pr. https://doi.org/10.1201/9781420050134.ch9

Masiello, P.; Broca, C.; Gross, R.; Roye, M. y Manteghetti, M. (1998). Experimental NIDDM development of a new model in adult rats administred streptozotocin and nicotinamide. Diabetes, 47. https://doi.org/10.2337/diab.47.2.224

Masiello, P. (2006). Animal models of type 2 diabetes with reduced pancreatic B-cell mass. The International Journal of Biochemistry and Cell Biology, 38: 873-893. https://doi.org/10.1016/j.biocel.2005.09.007

Mathis, D.; Vence, L.; Benoist, C. (2001). B-cell death during progression to diabetes. Diabetes Care, 414: 792-798. https://doi.org/10.1038/414792a

Matsuda, M. y DeFronzo, R. (1999). Insulin sensitivity indices obtained from oral glucosa tolerance testing. Diabetes Care, 22: 1462-1470. https://doi.org/10.2337/diacare.22.9.1462

Mendívil, A. y Sierra, A. (2005). Acción insulínica y resistencia a la insulina: aspectos moleculares. Revista de la Facultad de Medicina Nacional de Co- lombia, 53 (4): 235-243.

Meyts, P.D. (2000). Isulin and its receptor: structure, function and evolution. Bio Essays, 26: 1351-1356. https://doi.org/10.1002/bies.20151

Morgan, N.G.; Cable, H.C.; Newcombe, N.R. y Williams, G.T. (1994). Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis. Bioscience Reprint., 14: 243-250. https://doi.org/10.1007/BF01209729

Muniyappa, R.; Lee, S.; Chen, H. y Quon, M. (2007). Current approaches for assesing insulin sensitivity and resistance in vivo: advantages. Limitations and appropiate usage. American Journal of Physiologcal Endocrinology Metabol., 294: 15-26.

Muniyappa, R.; Chen, H.; Muzumadar, R.; Einstein, F.; Yan, X.; Yue, L.; Barzilai, N. y Quon, M. (2009). Comparision between surrogate indexes of insulin sensitivity/ resistance and hyperinsulinemic euglycemic clamp estimates in rats. American Journal of Physiological Endocrinology Metabol., 297: 1023-1029. https://doi.org/10.1152/ajpendo.00397.2009

Myers, M.G. y White, M.F. (2003). The new elements of insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains. Diabetes, 42: 643-650.

Nawrot, P.; Jordan, S.; Eastwood, J.; Rotstein, J.; Hugenholtz, A. y Feeley, M. (2003). Effects of caffeine on human health. Fodd Addition Contamination, 20 (1): 1-30. https://doi.org/10.2337/diabetes.42.5.643

Norma Oficial Mexicana (NOM-015-SSA2-1994). Para la prevención, tratamiento y control de la diabetes mellitus en la atención primaria. Disponible en http://www.guanajuato.gob.mx/ssg/prescripcion/normas/015SSA24. pdf.

Norma Oficial Mexicana (NOM-062-ZOO-1999). Especificaciones técnicas para la producción, cuidado y uso de animales de laboratorio. Disponible en http://www.guanajuato.gob.mx/ssg/prescripcion/normas.

Pass, D. y Freeth, G. (1993). The rat. An ZCCART, 6: 1-4.

Pirola, L.; Johnston, A.M. y Van Obberghen, E. (2004). Modulation of insulin action. Diabetologia, 47: 170-184. https://doi.org/10.1007/s00125-003-1313-3

Pons, S.; Asano, T.; Glasheen, E.; et al. (1995). The structure and function of p55PIK reveals a new regulatory subunit for phosphatidylinositol 3-kinase. Molecular Cell Biology, 15: 4453-4465. https://doi.org/10.1128/MCB.15.8.4453

Ross, G.W.; Abbott, R.D.; Petrovitch, H.; et al. (2000). Association of coffee and caffeine intake with the risk of parkinson disease. JAMA, 283: 26742679. https://doi.org/10.1001/jama.283.20.2674

Sakamoto, K.; Aschenbach, W.G.; Hirshman, M.F.; et al. (2003). Akt signaling in skeletal muscle: regulation by exercise and passive stretch. American Journal of Physiology Endocrinology Metabol., 285: 1081-1088. https://doi.org/10.1152/ajpendo.00228.2003

Schenk, S.; Saberi, M. y Olfesky, J.M. (2008). Insulin sensitivity: modulation by nutrients and inflamation. Journal of Clinical Investigation, 118: 29923002. https://doi.org/10.1172/JCI34260

Shafrir, E. y Ziv, E. (1998). Cellular mechanism of nutritionally induced insulin resistance: The dessert rodent Psamomys obesus and other animals in which insulin resistance leads to determental outcome. Journal of Basic Clinical Physiology and Pharmacology, 9: 347-385. https://doi.org/10.1515/JBCPP.1998.9.2-4.347

Shafrir, E.; Ziv, E. y Mosthaf, L. (1999). Nutritionally induced insulin resistance and receptor defect leading to B-cell failure in animal models. Ann. New York Academic Science, 892: 223-246. https://doi.org/10.1111/j.1749-6632.1999.tb07798.x

Shafrir E. (2007). Animal models of diabetes. Frontiers in research. 2nd Ed. Estados Unidos: CRC Press Taylor Francis. https://doi.org/10.1201/9781420009453

Shoelson, S.E.; White, M.F. y Kahn, C.R. (1998). Tryptic activation of the insulin receptor. Proteolytic truncation of the alfa-subunit releases the beta- subunit from inhibitory control. Journal of Biologgical Chemestry, 263: 4852-4860. https://doi.org/10.1016/S0021-9258(18)68864-7

Skolnik, E.Y.; Lee, C.H.; Batzer, A.; et al. (1993). The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: Implications for insulin control of ras signalling. EMBO Journal, 12: 1929-1960.

Smith, B.; Wingard, D.L.; Smith, T.C.; Kritz-Silverstein, D. y Barret-Connor, E. (2006). Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose? Diabetes Care, 29 (11): 2385-2390. https://doi.org/10.2337/dc06-1084

Srinivasan, K. y Ramarao, P. (2007). Animal models in type 2 diabetes research. Indian Journal of Medical Research, 125: 451-472.

Stalmach, A.; Mullen, W.; Barron, D.; Uchida, K.; Yokota, T.; Cavin, C.; Steling, N.; Williamson, G. y Crozier, A. (2009). Metabolite profiling of hidroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: Identification of biomarkers of coffee consumption. Drug Metabolism and Disposition, 37: 1-10.

Szkudelski, T. (2001). The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res., 50 (6): 537-546. https://doi.org/10.33549/physiolres.930111

Tuomilehto, J.; Lindstrom, J.; Eriksson, J.G.; et al. (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New England Journal of Medicine, 344: 1343-1350. https://doi.org/10.1056/NEJM200105033441801

Tuomilehto, J.; Hu, G.; Bidel, S.; Lindström, J. y Jousilahti, P. (2004). Coffee consumption and risk of type 2 diabetes mellitus among middle-aged finish men and women. JAMA, 291 (10): 1213-1219. https://doi.org/10.1001/jama.291.10.1213

Van Dam, R.M. y Hu, F.B. (2005). Coffee consumption and risk of type 2 diabetes: A systematic review. JAMA, 294: 97-104. https://doi.org/10.1001/jama.294.1.97

Van Dam, R.M.; Manson, J.E.; Willett, W.C. y Hu, F. (2006). Coffe, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women. Diabetes Care, 29 (2): 398-403. https://doi.org/10.2337/diacare.29.02.06.dc05-1512

Weyer, C.; Bogardus, C.; Mott, D.M. y Pratley, R.E. (1999). The natural history of insulin secretory disfunction and insulin resistance in the phatogenesis of type 2 diabetes mellitus. Journal of Clinical Investigation, 104: 787-794. https://doi.org/10.1172/JCI7231

Wojtaszewski, J.F.; Nielsen, P.; Kiens, B.; et al. (2001). Regulation of glycogen synthase kinase-3 in human skeletal muscle: effects of food intake and bicycle exercise. Diabetes, 50: 265-269. https://doi.org/10.2337/diabetes.50.2.265

World Health Organization (2009). Screening for type 2 diabetes. Report of a World Health Organization and International Diabetes Federation Meeting, WHO/NMH/MNC/03.1.

Yoshida, Y.; Haykawa, M. y Niki, E. (2008). Evaluation of the antioxidant effects of coffee and its components using the biomarkers hydroxyoctadecadienoic acid and isoprostane. Journal of Oleo Science, 12: 691-697. https://doi.org/10.5650/jos.57.691

Zheng, D.;McLean, P.; Pohnert, S.; Knight, J.; Olson, A.; Winder, W. y Dhom, G. (2001). Regulation of muscle GLUT -4 transcription by AMP- activated protein kinase. Journal of Applicated Physiology, 91: 1073- 1083. https://doi.org/10.1152/jappl.2001.91.3.1073

Portada con escena de laboratorio y jeringa aplicada a un animal, con fondo de patrones circulares, relacionada con investigación sobre cafeína y diabetes.

Publicado

15 enero 2015

Licencia

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.

Detalles sobre el formato de publicación disponible: Mi Tienda Ucol

Mi Tienda Ucol

Dimensiones físicas

Detalles sobre el formato de publicación disponible: Versión impresa

Versión impresa

ISBN-13 (15)

978-607-8356-30-0

Fecha de publicación de la versión impresa (19)

15-01-2015

Dimensiones físicas

16cm x 22.5cm

Cómo citar

Urzúa García, Z. (2015). Cafeína: Factor protector en la diabetes. Universidad de Colima. https://libros.ucol.mx/index.php/dgp/catalog/book/185